Effect of alcohol consumption on kidney function: population-based cohort study Scientific Reports

In this review, we focused on the effect of ethyl alcohol on the kidneys and the effect of drinking on patients with CKD, and summarized the clinical and experimental studies. We analyzed and compared the advantages and disadvantages of alcohol consumption for patients with CKD and the contradictions in existing studies, and we hope to provide some information for clinical decision-making and policy formulation. Drinking alcohol can affect many parts of your body, including your kidneys.

Results

The secondary outcome was a rapid decline in kidney function, defined as a decrease in the eGFR ≥ 20 mL/min/1.73 m2 over 12 years. The eGFR was calculated according to the CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration) equation17. That said, epidemiological data have yet to confirm a relationship between alcohol consumption and chronic kidney disease. A recent meta-analysis (Cheungpasitporn et al. 2015) found little support for such a relationship. Their analysis included 20 studies representing a total of 292,431 patients.

A little alcohol—one or two drinks now and then—usually has no serious effects. Drinking heavily can increase the risk of high blood pressure and Type 2 diabetes, for example. Both of those conditions are the most common causes of chronic kidney disease in the United States.

1. Healthy kidneys ensure that such proteins stay out of a normal urine flow; kidneys suffering from chronic alcohol abuse, on the other hand, cannot stop proteins (like albumin) from “leaking” into urine.
2. These hormones help stimulate red blood cell growth and regulate blood pressure.
3. Nowadays, many forms of ethyl alcohol are available, such as beer, wine, vodka, and other spirits, and these have become very popular among adults.
4. NO is a free gaseous signal molecule produced by the NOS family, including neuronal NO synthase (nNOS), inducible NO synthase (iNOS), and endothelial NO synthase (eNOS), and it plays an important role in hemodynamics regulation.
5. This involves breaking the physical hold of alcohol on the individual and then providing psychological and social care to ensure that alcohol no longer presents a medical or mental health risk.

Preventing interactions

This involves breaking the physical hold of alcohol on the individual and then providing psychological and social care to ensure that alcohol no longer presents a medical or mental health risk. Other issues, like a family history of related conditions (not limited to kidney problems, such as obesity, heart and/or cardiovascular issues, high blood pressure, or genetics) make some people more inclined toward the development of kidney failure than others. Alcohol, whether in moderation or excess, exacerbates kidney problems to the point of actual kidney disease. Although light-to-moderate alcohol consumption may not pose a risk to patients with xanax replacement CKD, the patients’ condition needs to be considered.

6. Study Design

Below are some answers to frequently asked questions about alcohol-induced kidney damage. The treatment for alcohol-induced kidney problems depends largely on the type of kidney disease a person has sustained. According to the American Kidney Fund (AKF), there are five stages of chronic kidney disease (CKD), with stage 1 representing the earliest and mildest stage and stage 5 representing the most advanced and severe.

Similarly, there’s minimal evidence to suggest that alcohol increases the risk of kidney stones or kidney infections. “We do know that people who don’t drink enough fluids have a greater chance of developing kidney stones.” So, people who drink heavily and are often dehydrated may be at greater risk — though the science of alcohol’s role in kidney stones is still unclear, he adds. What about the kidney pain some people claim to feel after a night of drinking?

Nonetheless, the reviewers note that alcohol metabolism produces free radicals and other harmful by-products that are known to damage the body’s organs and tissues. This article describes how alcohol may harm the kidneys and considers the level of alcohol consumption necessary to cause harm. AKF works on behalf of 1 in 7 Americans living with kidney disease, and the millions more at risk, to support people wherever they are in their fight against kidney disease — from prevention through post-transplant living. A person is at risk of different complications depending on the underlying cause of the kidney pain.